PIVKA-II stands for Protein Induced by Vitamin K Absence or Antagonist-II.
It is a blood test used primarily to detect and monitor Hepatocellular Carcinoma (HCC) — the most common type of primary liver cancer.

It serves as a tumor marker, especially when used along with Alpha-Fetoprotein (AFP), for better accuracy.

Why is the PIVKA-II Test Done?

✅ To detect liver cancer in its early stages
✅ To monitor recurrence after treatment of HCC
✅ To differentiate between malignant and benign liver diseases
✅ In patients with chronic liver disease (e.g., hepatitis B or cirrhosis)